梁新軍,醫學博士,湖北省腫瘤醫院主任醫師,碩士生導師
研究方向
腫瘤免疫逃逸機制;腫瘤表觀遺傳機制
代表論文
1. Fu C, Liang X, Cui W, Ober-Blöbaum JL, Vazzana J, Shrikant PA, Lee KP, Clausen BE, Mellman I, Jiang A. β-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2823-8. doi: 10.1073/pnas.1414167112. Epub 2015 Feb 17. PMID: 25730849; PMCID: PMC4352820.
2. Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. β-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8⁺ T cells. J Leukoc Biol. 2014 Jan;95(1):179-90. doi: 10.1189/jlb.0613330. Epub 2013 Sep 10. PMID: 24023259.
3. Pang S, Zhou Z, Yu X, Wei S, Chen Q, Nie S, Liang X, Liu L. The predictive value of integrated inflammation scores in the survival of patients with resected hepatocellular carcinoma: A Retrospective Cohort Study. Int J Surg. 2017 Jun;42:170-177. doi: 10.1016/j.ijsu.2017.04.018. Epub 2017 Apr 13. PMID: 28414120.
主要科研項目
1. 國家基金委:補體C3調控巨噬細胞自噬促進肺癌轉移的作用和機制,55萬元,2018.7-2021.12,主持人
2. 國家基金委:肺癌DCs中β-catenin上調抑制自噬誘導CD8+T細胞耐受及其機制,78萬元,2016.1-2019.12,主持人